RAD140 – Solution, 10mg x 30mL

RAD140 – Solution, 10mg x 30mL

$60.00

10mg per mL, 300mg/30mL total; includes 1mL pipette

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SKU: rad140-solution Categories: , Tags: , , ,
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Read the Specification Before Buying:

ApplicationSelective Androgen Receptor Modulator
CAS1182367-47-0
Molar Mass393.83 g/mol
 Chemical FormulaC20H16ClN5O2
Chemical Name2-chloro-4-{[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino}-3-methylbenzonitrile
SynonymsRAD140, RAD-140
StorageRoom temperature
SolubilityEthanol, PEG
Organoleptic ProfileClear Liquid
Physical FormSolution in Ethanol, PEG
Reports1HNMRLCMS
TermsThe products we offer are intended for laboratory research use only.
Please familiarize yourself with our Terms & Conditions prior to ordering.

Literature

  1. Jayaraman A, Christensen A, Moser VA, Vest RS, Miller CP, Hattersley G, Pike CJ (Apr 2014).“Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats”. Endocrinology 155 (4): 1398–406. doi:10.1210/en.2013-1725.PMC 3959610. PMID 24428527.
  2. Hamson DK, Wainwright SR, Taylor JR, Jones BA, Watson NV, Galea LA (Sep 2013). “Androgens increase survival of adult-born neurons in the dentate gyrus by an androgen receptor-dependent mechanism in male rats”. Endocrinology 154 (9): 3294–304. doi:10.1210/en.2013-1129.PMID 23782943.
  3. Miller CP, Shomali M, Lyttle CR, O’Dea LS, Herendeen H, Gallacher K, Paquin D, Compton DR, Sahoo B, Kerrigan SA, Burge MS, Nickels M, Green JL, Katzenellenbogen JA, Tchesnokov A, Hattersley G (Feb 2011). “Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140”. ACS Medicinal Chemistry Letters 2 (2): 124–9. doi:10.1021/ml1002508. PMC 4018048. PMID 24900290.
  4. Chris Miller, Maysoun Shomali, C Richard Lyttle, Gary Hattersley (24 June 2012). “SUN-525: A Selective Androgen Receptor Modulator (RAD140) Induces Inflammation in Rat Right Heart Ventricle: Evidence for an Androgen-Specific, Species-Specific Mechanism”. The Endocrine Society’s 94th Annual Meeting and Expo, June 23–26, 2012 – Houston, TX. Endocrine Society. Retrieved 19 October 2015.